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Mytĭlēnē (in later times Mĭtylēnē), ēs, f., and Mytĭlēnae, ārum, f., = Μυτιλήνη, the capital of Lesbos, the birthplace of Sappho, Pittacus, Alcæus, and Diophanes, the orator, now Mytilini or Castro.
Mytilene: laudabunt alii claram Rhodon, aut Mytilenen, Hor. C. 1, 7, 1; id. Ep. 1, 11, 17 al.
In plur. form, Mytilenae: Mytilenis an Rhodi malles vivere, Cic. Agr. 2, 16, 40; id. Fam. 4, 7, 4; Suet. Caes. 2; id. Aug. 66; id. Tib. 10; Caes. B. C. 3, 102, 5.